Make the cocktail sauce by combining the ketchup and wasabi horseradish to taste and mixing until well combined. Set aside to allow flavors to mingle.
Dredge the oysters by combining the panko seasonings with fresh parsley, garlic powder, sea salt, and freshly cracked pepper to taste.
Heat the butter and oil in a large nonstick skillet over medium-high heat.
Dip the oysters, one at a time, in the panko crumbs, coating the entire oyster evenly.
Cook the oysters by immediately placing them into the HOT skillet. Repeat with the remaining jar of oysters, making sure not to overcrowd the pan. Cook until golden brown, about 2 minutes.
Carefully flip the oysters over and continue cooking until golden brown and crisp, about 1-2 minutes.
Remove the oysters from the skillet and place them on a paper towel-lined plate to drain some of the grease.
Serve immediately, along with lemon wedges and cocktail sauce. Enjoy!